For years, my sinuses would close up during the night and I would wake up struggling to breathe. This was with nasal strips and nasal sprays. After eight hours in the system (four 2-hour sessions), I noticed my sinuses were staying open and I was sleeping through the night. I no longer use the nasal strips and I have severely cut back on the nasal spray with intentions of stopping completely very soon. I also have presbyopia for the last five years or so. After about 14 hours in the system, I was able to notice improvement with my vision while reading the computer. And about 10 more hours after that, the improvement has become consistent. I am much less dependent on the reading glasses now.